If you are keen on gathering more info on the fitness and health industry, you might have stumbled upon the name RAD-140 which is also known as Testolone. Being one of the Selective androgen receptor modulators (SARMs) Testolone is quite popular among fitness and bodybuilding enthusiasts.
Simply put, SARMs are effective at building muscles similarly to androgenic steroids. Not to mention, SARMs such as Testolone are believed to hinder muscle wasting and skeleton wasting conditions such as Osteoporosis.
However, is it safe to use, and are there scientifically proven benefits? Let’s find out.
- Treating Loss of Muscle Mass
According to James Dalton, PhD, dean of pharmaceutical sciences at the University of Michigan, SARMs are different from commonly used androgenic steroids because of their capability of stimulating muscle and bone growth with the least prostatic effects in males.
Moreover, as stated in ncbi.nlm.nih.gov, Testolone which is one of the potent anabolic SARMs has antagonistic effects on the prostate and seminal vesicles. In other words, these qualities show that RAD-140 is a well-suited solution for muscle and bone growth.
On the other hand, gaining muscle mass becomes a tricky job when it doesn’t only depend on the way we eat or exercise. If there is an abnormality in one’s genes, it is indeed quite difficult to deal with. However, SARMs show a promise of treating muscular dystrophies. Here, the abnormal genes (mutations) obstruct the production of proteins that are required to build healthy muscle. The ncbi.nlm.nih.gov further suggests that SARMs administered to patients with Duchenne muscular dystrophy (DMD) would significantly increase protein synthesis levels and muscle mass.
- RAD-140 has a Neuroprotective Potential
In studies conducted on determining whether RAD-140 or Testolone has a neuroprotective potential, researchers found that in fact, RAD-140 protects cultured neurons. This confirms that RAD-140 has managed to reduce cell death.
Neurodegeneration is a state that affects neurons in the human brain. The worst-case scenario is, brain damage, paralysis from spinal cord injury, and peripheral nerve damage are usually permanent, and the patients need constant care and lifelong assistance.
Therefore, using RAD-140 may fight neuronal death and protect humans from brain-related diseases.
- Treating Benign Prostatic Hyperplasia
Another crucial finding regarding RAD-140 is its efficacy in treating Benign prostatic hyperplasia (BPH). This condition is also known as prostate gland enlargement that occurs when men get older. It tends to cause uncomfortable urinary symptoms including the blockage of urine flow out of the bladder and emerge bladder, urinary tract, or kidney problems.
Research results conducted on Benign prostatic hyperplasia conclude that SARMs, in particular, can be used as possible adjuncts or monotherapy for Benign prostatic hyperplasia that is of course with minimal side effects.
- May be Beneficial for Weight Gain (Fat-Free Mass)
According to another article published on ncbi.nlm.nih.gov, the researchers have conducted a thorough study on evaluating anabolic, lipid, and other clinical chemistry parameters by testing RAD-140 in young male monkeys.
This 28-day study was carried out by giving RAD-140 doses to the subjects. Incredibly, a mean weight gain that is greater than 10% was achieved just in 28 days of giving a Testolone dose of 0.1 mg/kg. The graph that is shown in this study displays a mammoth spike of body weight gain within the dosing period.
The study also suggests that the overall preclinical profile of RAD-140 is up to par and has completed the preclinical toxicology in both rats and monkeys as well. The researchers also mention that they are hoping to commence phase I clinical studies with RAD-140 to observe the benefits of it toward the patients suffering from severe weight loss because of cancer cachexia.
The fact that RAD-140 is being experimented with for curing cancer patients is groundbreaking. This further proves the potential of Testolone which is linked to accelerating weight gain and building lean muscle mass. The takeaway is, RAD-140 may be a safer way of treating such diseases.
- May Suppress the Growth of Breast Cancer
This might be the most intriguing piece of research result that has come to the spotlight regarding the impeccable potential benefits of Testolone. As one of the most effective SARMs out there, researchers have been keeping an eye on RAD-140 for its potential to be used for suppressing the growth of breast cancer.
Breast cancer is the second leading culprit for cancer-related deaths in women. As a matter of fact, in 2016, there were 246,660 newly diagnosed cases of breast cancer, and 40,450 deaths were reported in the United States alone.
Although breast cancer is currently treated with novel therapeutic approaches, further research is being carried out in order to scrutinize and augment the chances of mitigating this fatal state.
As mentioned in the American Association for cancer research, RAD-140 was evaluated for its effectiveness in breast cancer and showed a significant level of antitumor activity. Needless to say, the study results conclude that RAD-140 as a single agent may be quite effective in inhibiting the growth of AR/ER+ breast cancer xenografts.
The bottom line is, the efficacy of Testolone monotherapy may potentially be a beacon of hope for millions of people out there in the world.
Over to You
Undoubtedly, RAD-140 holds a vast promise for being a new class of function that promotes anabolic therapies for many clinical indications. Especially, various studies such as the ones mentioned above show optimistic results on RAD-140 for functional limitations that come along with aging, chronic disease, frailty, cancer cachexia, and osteoporosis.
More importantly, if you are passionate about health and fitness, remember that your well-being comes in a package. The mere gain of muscle mass will not help you achieve what you truly need. In order to maintain your mental and physical equilibrium, you should keep your overall body healthy in check. This is why SARMs such as Testolone may be promising in delivering desirable fitness results with less health potential health risks than traditional anabolic supplements.
However, keep in mind that RAD-140 products out there in the market are sold for research purposes. 33% of SARMs sold may be fake or underdosed. So, if you are opting for one (for research purposes only, not for human use), make sure to choose a legitimate RAD-140 product, that will meet your standards.